Neurogenesis • October 16, 2026
Psilocybin and Adult Hippocampal Neurogenesis: Memory Consolidation and Structural Recovery
Preclinical and human biomarker data reveal that psilocybin promotes progenitor cell proliferation in the hippocampal dentate gyrus, reversing stress-induced atrophy.
Stress-Induced Atrophy of the Hippocampus
Chronic psychological distress suppresses neurogenesis in the subgranular zone of the dentate gyrus, impairing context-dependent memory and emotional regulation.
Progenitor Cell Proliferation and Dentate Gyrus Plasticity
Low-to-moderate doses of psilocybin stimulate neural progenitor cell division and maturation into functional dentate granule neurons, promoting cognitive adaptability.