Eating Disorders • September 12, 2026
Anorexia Nervosa and Eating Disorders: Resetting Insular Cortical Body Representation
Clinical trials at Johns Hopkins show 40%+ of severe anorexia nervosa patients achieved significant weight restoration and body dysmorphia reduction post-psilocybin.
The Highest Mortality Rate in Psychiatry
Anorexia nervosa has the highest mortality rate of any psychiatric condition, driven by rigid cognitive distortions, extreme anxiety around eating, and insular cortex dysfunction.
UCSD & Johns Hopkins Clinical Trial Data
In clinical safety trials at UCSD, a single 25mg psilocybin session combined with therapeutic support led to dramatic shifts in eating disorder core beliefs and body distortion metrics.